Yi-Ching Wang Selected Research

Proteins (Proteins, Gene)

2/2024	Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer.
1/2023	Nutlin-3 acts as a DNA methyltransferase inhibitor to sensitize esophageal cancer to chemoradiation.
12/2022	Secretory autophagy promotes Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1.
9/2022	Emerging roles of plasma gelsolin in tumorigenesis and modulating the tumor microenvironment.
1/2022	Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression.
1/2022	Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy.
1/2021	Converged Rab37/IL-6 trafficking and STAT3/PD-1 transcription axes elicit an immunosuppressive lung tumor microenvironment.
6/2020	ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer.
1/2020	Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression.
1/2019	Oncogenic zinc finger protein ZNF322A promotes stem cell-like properties in lung cancer through transcriptional suppression of c-Myc expression.

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Yi-Ching Wang Research Topics

Disease

82	Neoplasms (Cancer) 03/2024 - 04/2002
56	Lung Neoplasms (Lung Cancer) 03/2024 - 04/2002
20	Neoplasm Metastasis (Metastasis) 05/2023 - 02/2005
17	Carcinogenesis 08/2023 - 04/2002
15	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2023 - 07/2004
13	Esophageal Squamous Cell Carcinoma 01/2023 - 11/2005
8	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2009 - 07/2004
7	Breast Neoplasms (Breast Cancer) 01/2019 - 08/2009
6	Adenocarcinoma of Lung 01/2022 - 02/2007
4	Esophageal Neoplasms (Esophageal Cancer) 01/2023 - 08/2012
4	Adenocarcinoma 01/2022 - 04/2002
3	Necrosis 01/2020 - 03/2004
3	Triple Negative Breast Neoplasms 01/2017 - 01/2013
3	Hepatocellular Carcinoma (Hepatoma) 02/2005 - 03/2004
2	Genomic Instability 03/2024 - 03/2008
2	Stroke (Strokes) 01/2023 - 11/2022
2	Mouth Neoplasms (Oral Cancer) 02/2017 - 09/2015
2	Squamous Cell Neoplasms (Squamous Cell Cancer) 08/2006 - 11/2005
2	Hemorrhage 03/2004 - 03/2004
1	Starvation 05/2023
1	Dementia (Dementias) 01/2023

Drug/Important Bio-Agent (IBA)

39	Proteins (Proteins, Gene)FDA Link 02/2024 - 04/2002
21	Messenger RNA (mRNA)IBA 10/2023 - 03/2003
18	DNA (Deoxyribonucleic Acid)IBA 10/2023 - 04/2002
15	Biomarkers (Surrogate Marker)IBA 02/2024 - 09/2006
9	Monomeric GTP-Binding ProteinsIBA 02/2024 - 03/2009
7	Histone Deacetylase InhibitorsIBA 01/2017 - 09/2010
6	MethyltransferasesIBA 01/2023 - 02/2007
6	Transcription Factors (Transcription Factor)IBA 10/2022 - 09/2014
6	Histone Deacetylases (Histone Deacetylase)IBA 01/2021 - 09/2010
5	EnzymesIBA 10/2023 - 02/2007
5	MicroRNAs (MicroRNA)IBA 08/2023 - 01/2014
5	Oncogene Proteins (Oncogene Protein)IBA 09/2022 - 08/2010
4	ChromatinIBA 10/2023 - 02/2007
4	Indicators and Reagents (Reagents)IBA 01/2019 - 09/2010
4	PaxillinIBA 05/2017 - 01/2008
4	beta CateninIBA 01/2010 - 03/2008
3	Tissue Inhibitor of Metalloproteinase-1IBA 05/2023 - 09/2014
3	nutlin 3IBA 01/2023 - 08/2012
3	Protein Isoforms (Isoforms)IBA 01/2022 - 10/2012
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 09/2015
3	CateninsIBA 01/2022 - 09/2014
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2020 - 09/2009
3	Actins (F Actin)IBA 12/2015 - 09/2010
3	Cisplatin (Platino)FDA LinkGeneric 04/2014 - 01/2007
3	beta-Transducin Repeat-Containing ProteinsIBA 02/2010 - 09/2009
3	ParaffinIBA 01/2010 - 05/2008
2	adducinIBA 08/2023 - 10/2019
2	Cyclin D1IBA 08/2023 - 10/2019
2	Amiodarone (Amiodarona)FDA LinkGeneric 05/2023 - 12/2022
2	CytokinesIBA 05/2023 - 12/2022
2	Matrix Metalloproteinases (MMPs)IBA 05/2023 - 01/2012
2	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 06/2020
2	RNA (Ribonucleic Acid)IBA 10/2022 - 01/2022
2	IronIBA 10/2022 - 01/2021
2	Estrogens (Estrogen)FDA Link 05/2022 - 01/2022
2	Estradiol (Delestrogen)FDA LinkGeneric 05/2022 - 01/2022
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 01/2013
2	benzamideIBA 01/2021 - 01/2012
2	Fibronectins (Fibronectin)IBA 11/2020 - 09/2012
2	VimentinIBA 11/2020 - 01/2011
2	Phosphotransferases (Kinase)IBA 06/2020 - 01/2010
2	Sirtuin 1IBA 02/2019 - 08/2009
2	Tissue Inhibitor of MetalloproteinasesIBA 11/2018 - 12/2017
2	Glycoproteins (Glycoprotein)IBA 12/2017 - 01/2010
2	TMU-35435IBA 01/2017 - 01/2017
2	Vorinostat FDA Link 10/2016 - 01/2013
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 06/2016 - 12/2011
2	Small Interfering RNA (siRNA)IBA 01/2016 - 08/2010
2	indoleIBA 08/2012 - 08/2008
2	SmokeIBA 03/2012 - 05/2006
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 12/2011 - 01/2010
2	Histones (Histone)IBA 09/2010 - 08/2006
2	CytosineIBA 07/2010 - 07/2004
2	Glycogen Synthase KinasesIBA 01/2010 - 03/2008
2	ErbB Receptors (EGF Receptor)IBA 09/2009 - 01/2008
2	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 07/2009 - 03/2008
2	Histidine (L-Histidine)FDA Link 11/2007 - 08/2006
2	Cyclin-Dependent Kinase Inhibitor p16IBA 02/2007 - 04/2002
2	Tumor Suppressor Protein p14ARF (p14ARF)IBA 01/2005 - 07/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2004 - 03/2004
2	Capsules (Microcapsules)IBA 03/2004 - 03/2004
1	Doxycycline (Periostat)FDA LinkGeneric 03/2024
1	Gefitinib (Iressa)FDA Link 03/2024
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 03/2024
1	B7-H1 AntigenIBA 03/2024
1	Tyrosine Kinase InhibitorsIBA 10/2023
1	UbiquitinIBA 10/2023
1	Ligases (Synthetase)IBA 10/2023
1	Cullin Proteins (Cullins)IBA 10/2023
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2023
1	Niclosamide FDA Link 01/2023
1	Hormones (Hormone)IBA 01/2023

Therapy/Procedure

16	Therapeutics 03/2024 - 01/2011
4	Drug Therapy (Chemotherapy) 01/2012 - 01/2007
3	Immunotherapy 01/2022 - 01/2020
2	Radiotherapy 10/2022 - 01/2017
2	Chemoradiotherapy 10/2022 - 06/2017
2	Intraperitoneal Injections 01/2013 - 01/2012
1	Activities of Daily Living (ADL) 01/2023